RESUMO
Malignant pleural mesothelioma is a relatively rare, but highly aggressive, tumor, associated to exposure to asbestos, with a life expectancy between 9 and 17 months. Chest pain and dyspnea are the most frequent symptoms. The most commonly used therapy is surgery accompanied by chemotherapy. Preoperative assessment, after chemotherapy, has been done using magnetic resonance imaging and computed tomography (CT). However, these techniques cannot predict early response to therapy, because of the slow structural change of the tumor. The aim of this case report is to review and learn about the growing use of PET-CT imaging with (18)F-FDG in the preoperative staging of malignant pleural mesothelioma and its influence in selecting the most appropriate type of surgery.
Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Radioisótopos de Flúor , Fluordesoxiglucose F18 , Mesotelioma/diagnóstico por imagem , Imagem Multimodal , Terapia Neoadjuvante , Neoplasias Pleurais/diagnóstico por imagem , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Tomografia Computadorizada por Raios X , Cisplatino/administração & dosagem , Terapia Combinada , Glutamatos/administração & dosagem , Guanina/administração & dosagem , Guanina/análogos & derivados , Humanos , Metástase Linfática , Masculino , Mesotelioma/tratamento farmacológico , Mesotelioma/secundário , Mesotelioma/cirurgia , Pessoa de Meia-Idade , Pemetrexede , Neoplasias Pleurais/tratamento farmacológico , Neoplasias Pleurais/cirurgia , Cuidados Pré-Operatórios , Carga TumoralRESUMO
Las fracturas del fémur distal son complejas en su tratamiento y asocian múltiples complicaciones evolutivas com pseudoartrosis, callos viciosos, gonartrosis o infección secundaria a cirugía abierta agresiva, por lo que han surgido las osteosíntesis mínimamente invasivas dentro de las cuales se sitúa la placa LISS. Analizamos los resultados tras 10 meses de seguimiento de 14 pacientes con fractura del fémur distal tratados con placa LISS. Los tiempos de consolidación no fueron muy divergentes respecto a series mayores, la incidencia de retrasos de consolidación y callos viciosos, baja. No hubo pseudoartrosis, fracasos del material, aflojamientos, infecciones, tromboembolismos ni algodistrofias. Por ello, consideramos que los resultados obtenidos con este implante son satisfactorios
The treatment of the distal femoral fractures is difficult in order to the surgery and múltiple complications, like pseudoartrosis,c allus vicious, gonartrosis or infection because open surgery. So that it has arised the minimun invasive system of osteosynthesis like LISS plate. We have assessed outcomes in 14 patients with distal femoral fractures treated with that implant. The mean follow up was 10 months. The times of consolidation was similar than other bigger series of patients and low incidence of delayed consolidation and callus vicious. There has not been any case of pseudoartrosis, failure of implant, loosenin, infections, tromboembolism or algodystrophia, so that considered that we has obtained good results
